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Neverness to Everness Iroi Build Guide - Best Builds, Skills, and More
2026-07-31

Meet Iroi, the first limited S-Rank dedicated healer in Neverness to Everness, who brings incredible support abilities to the battlefield. She is not just a normal healer but also provides powerful Attack buffs that increase the team's damage, grants DEF Ignore effects, and protects allies through her unique Regression mechanic. Her excellent synergy with multiple reaction teams also makes her a valuable addition for many players. However, before pulling for her, understanding Iroi's full kit, Iroi best builds, and strengths in battle is important.

Neverness to Everness Iroi Build Guide

To help you, this Neverness to Everness Iroi build guide covers everything you need to know about creating the best Iroi build, including her skills, Arc options, Cartridge/Modules, Awakening priorities, rotations, and recommended teams. Improving your gameplay with Iroi comes from testing different rotations and team combinations, and with OSLink, you can play your Neverness to Everness PC session remotely from your mobile device, making it easier to farm Iroi materials and continue your NTE adventure anytime, anywhere.

Neverness to Everness Iroi Overview 

Rarity: S-Rank

Esper Type: Anima

Arc Type: Liquid

Role: Support / Healer / Buffer

Gender: Female

Specialty: Team healing, Regression mechanic, ATK buffs, DEF Ignore support, and team reviving ability

Strength: Exceptional team sustain, powerful offensive buffs, unique revive mechanic, excellent synergy with Blossom, Charge, and Hexed reaction teamsNeverness to Everness Iroi Overview

Iroi is the first limited S-Rank dedicated healer who comes as a new member of the Neverness to Everness roster. Rather than functioning as a traditional healer, she provides both powerful team survivability and strong attack buffs, making her an excellent offensive support character. Also, her unique Regression mechanic prevents teammates from being defeated by placing them into a protected state until her Ultimate restores them, making the most difficult encounters much easier to handle.

With her effective healing, defensive utility, and ATK-scaling kit, Iroi is currently considered one of the best support characters that fits into multiple top-tier team compositions.

How to Obtain Iroi: Iroi is available on The Lifeline Limited Board (Exclusive Iroi banner) that runs from July 29th to August 19th. She is the second limited S-Rank Esper introduced in Neverness to Everness Version 1.2 after Shinku.

Iroi Skill Breakdown

The best way to get started with Iroi for your adventure is by understanding how her kit works in battles. Iroi's entire kit runs on building up Imagination, which is filled up through Basic Attacks and skills to trigger her Ultimate. Once the Imagination resource is fully charged, she can unleash powerful healing and offensive abilities to provide huge support to the team. Here's the full details on how Iroi's kit works:

Basic Attack - Collaboration

Iroi performs a 5-hit Basic Attack combo that deals Liquid Anima Damage while generating a unique resource called Imagination.Basic Attack - Collaboration

  • Every Basic Attack builds Imagination, which is required to unlock the full effects of her Ultimate.
  • Imagination Gauge: You can see it above the HP bar. Once it is fully charged, Iroi can consume it with her Ultimate to activate additional off-field Anima damage.
  • Basic Attacks are mainly used to build Imagination during longer fights.

Iroi Skill - Future Self Continuity

This is Iroi's most important offensive ability, which can be used in every rotation for building up Imagination. After activating her Skill, she can:Iroi Skill - Future Self Continuity

  • Heal nearby teammates.
  • Summon Dream Lambs that remain on the battlefield and continuously deal Anima damage.
  • Holding the Skill: Places up to three teammates into Regression (Regression state helps them stay in battle without being defeated) that can be revived later through her Ultimate.
  • Pull nearby enemies together, making it easier for teammates to hit multiple targets.
  • Grant the entire team an Attack buff, providing 20% Attack for 20 seconds.

This Skill provides healing, crowd control, and one of the strongest Attack buffs in the game with a single cast.

Ultimate - 3.8-Billion-Year Mirage 

Iroi's Ultimate changes depending on the amount of Imagination she has stored.Ultimate - 3.8-Billion-Year Mirage

  • Low Imagination → Opens Dream of the Horned Gate: Continuously heals all teammates.
  • High/Full Imagination → Opens Dream of the Ivory Gate: Continuously deals Anima damage to enemies and can revive a teammate in the Regression state.

Another important advantage is that during her Ultimate, Charged Attacks no longer consume Imagination, allowing you to maximize damage without losing resources.

Iroi Passive Skills 

Iroi's Passive Skills are the ones that help maximize her offensive and defensive abilities much more than a traditional healer.Iroi Passive Skills

  • Mirror Image: This is a Blossom Enhancement that helps Iroi trigger her passive effect whenever she creates an additional Vita Bud. This does not count toward the normal Vita Bud limit, significantly increasing Blossom reaction damage.
  • Sympathetic Nerves: This is a DEF Ignore buff that helps the entire team gain 5% Defense Ignore for 20 seconds, allowing all teammates to deal more damage against enemies whenever Iroi heals an ally.

Iroi's Skill Upgrade Priority 

Follow this upgrade order to get the best performance from Iroi during battles:Iroi's Skill Upgrade Priority

  1. Ultimate: Her main strength for providing higher team healing, revive mechanics, and high-Imagination damage effects. Level this up first.
  2. Skill: Helpful for every rotation to provide the team Attack buff and Imagination generation.
  3. Basic Attack: Helps build Imagination.
  4. Support Skill: Adds extra healing and utility support for the team during quick character swaps.

How to Play Iroi (Simple Rotation) 

You have learned about how Neverness to Everness Iroi's kit works. Now, it's time to master Iroi's rotation to understand how to use her perfectly within your battles.How to Play Iroi (Simple Rotation)

  • First, start with Iroi and use her Basic Attacks to build Imagination.
  • Use her Skill and hold it to apply Regression effects to the teammates.
  • Swap to your main DPS in the team and run their full damage window while the Attack buff and Regression effects are active.
  • Again, swap back to Iroi to heal the team with her Skill.
  • Trigger Iroi's Ultimate when a teammate falls down to use the revive ability or when Imagination is filled up to deal extra Anima DMG.
  • Repeat this rotation, focusing on building Regression and using the Ultimate at the right times.

Battle Tip: Don't spend too much time building Imagination in every rotation. For most battles, simply using Iroi's Skill before swapping to your main DPS provides the highest overall team damage, while saving her Ultimate for longer fights or when additional healing is needed.

Iroi Awakenings and Resonance 

Iroi's Awakenings improve her healing, support capabilities, and even increase her personal damage. While she performs exceptionally well at A0, investing in her Awakenings can further increase both her team utility and off-field damage. Below are the details of her Awakenings and their effects:

Awakening Effect Why It Matters

A1

A1

Generates Imagination while Iroi is off-field and increases Imagination generation by 30%. Best early upgrade for smoother Ultimate rotations and sub-DPS builds.

A2

A2

Triggers an additional assist attack and increases Iroi's personal damage. Provides a noticeable DPS increase during combat.

A3

A3

Improves Iroi's healing effectiveness. Makes team survivability even stronger in difficult content.

A4

A4

Increases Iroi's personal damage. Best Awakening for players building her as a damage-focused support.

A5

A5

Grants the team an additional 15% Attack buff. One of her strongest support upgrades and greatly boosts overall team damage.

A6

A6

Revived teammates return with 100% HP, while also restoring Energy. Excellent quality-of-life upgrade for difficult boss fights and endgame content.

Awakening Priority 

A5 → A1 → A6 → A4 → A2 → A3

  • A5 is the best overall upgrade, granting an additional 15% Attack Buff that greatly increases your entire team's damage.
  • A1 is the best early investment for sub-DPS builds, allowing Iroi to generate Imagination while off-field for more frequent Ultimate usage.

Awakening Priority

Unlocking Iroi's A5 and A1 mostly helps increase her offensive abilities while supporting the team with ATK buffs and healing abilities.

Stats Priority for Iroi

Iroi's healing and support abilities scale primarily with Attack, therefore the Stat Priority for Iroi should focus on increasing her offensive stats instead of building HP like a traditional healer. Below is the Stat priority and reason:Stats Priority for Iroi

Recommended Stats Priority: Attack % > Flat Attack > Anima Damage Bonus > Energy Regeneration > Healing Bonus > HP > Defense

  • Attack % – Her most important stat, increasing healing, buffs, and damage.
  • Flat Attack – Provides additional Attack.
  • Anima Damage Bonus – Increases her personal damage.
  • Energy Regeneration – Helps recharge her Ultimate faster.
  • Healing Bonus – Useful if your team needs extra sustain.
  • HP – Improves survivability but isn't a priority.
  • Defense – Lowest priority.

Best Iroi Arcs (Weapons) 

The best Arcs for Iroi are the ones that increase stats like ATK, healing, Anima DMG, and team-wide buffs. Because Iroi's healing scales with ATK stats and she also contributes solid off-field damage, these weapons, including her Signature Arc, help create the best Neverness to Everness Iroi builds to maximize her supportive role.

Arc Effect Why It Matters

Wrong Gate (Signature Arc)

Wrong Gate (Signature Arc)

Increases ATK and, after healing, boosts Anima DMG by 30% and all allies' damage by 15%. Best-in-slot. Maximizes Iroi's healing, personal damage, and team-wide support.

Youthful Fantasy (Alternative Arc)

Youthful Fantasy (Alternative Arc)

Provides high ATK and improves overall offensive performance. Strong alternative that increases both healing and damage output.

Call of the Twisted City (4★)

Call of the Twisted City (4★)

Grants useful offensive stats that improve Iroi's overall performance. Great free-to-play option.

Clear Skies (4★)

Clear Skies (4★)

Increases ATK and offers balanced offensive stats. A solid early-game choice until stronger Arcs become available.

Best Iroi Cartridge / Modules Set Up 

When you're trying to create the best Neverness to Everness Iroi build, focus on Iroi Modules that improve ATK, Anima DMG, healing, and overall team support. You can use these Module sets to make her the best supportive character for your adventure.

Module Effect Why It Matters

Speedy Hedgehog

2-Piece: Increases ATK.4-Piece: After casting Ultimate, grants an additional Attack buff to the entire team. Best support set for Iroi. It further strengthens her team-wide buffs and increases overall party damage.

Fireflies and the Forest

Fireflies and the Forest

2-Piece: Increases Anima DMG.4-Piece: Further boosts Iroi's personal damage during combat. Best option for players building Iroi as a sub-DPS while maintaining strong healing capabilities.

Best Iroi Team Recommendations 

Iroi is a powerful Liquid Anima Support who works best in reaction-based teams that need strong healing, Attack buffs, and additional Anima damage. Also, as an Anima character, she can enhance Blossom (Cosmos + Anima), Charge (Lakshana + Cosmos + Anima), and Hexed (Anima + Incantation) reactions. Therefore, focus on building her teams with characters that can take advantage of her buffs and help trigger powerful elemental reactions.Best Iroi Team Recommendations

Shinku Premium Burst Team 

This is one of the strongest Iroi teams for boss fights and difficult endgame content that triggers Charge and Blossom reaction effects. It allows Shinku (Main DPS) to maximize her Crimson Ascension uptime, while Iroi provides powerful buffs and team survival through Regression.

Character Role Why They Work Well
Shinku (Cosmos) Main DPS The team's primary damage dealer, dealing massive Cosmos damage during Crimson Ascension.
Hathor (Lakshana) Sub DPS / Reaction Support Helps trigger Remora reactions and increases Shinku's damage through additional burst damage.
Zero (Cosmos) Reaction Support Generates Cycle Energy quickly and keeps the team's reaction rotation active.
Iroi (Anima) Support / Healer Provides Attack buffs, healing, Defense Ignore buffs, and Regression protection for Shinku.

Iroi Blossom Team 

This team focuses on consistent Blossom reaction damage and provides a strong option for players who do not use Shinku. Iroi improves the team's damage output while providing reliable healing for longer fights.

Character Role Why They Work Well
Nanali (Cosmos) Main DPS Deals consistent damage by increasing Blossom attack frequency.
Jiuyuan (Anima) Sub DPS / Reaction Support Creates additional Blossom Buds and improves reaction damage.
Zero (Cosmos) Support Keeps Cycle Energy generation high and helps maintain reaction uptime.
Iroi (Anima) Support / Healer Boosts team Attack, provides healing, and increases overall damage through buffs.

Should You Pull Iroi? 

Iroi's pull advice is simple, and the answer is yes. Iroi is one of the best support characters in Neverness to Everness, making her a valuable choice for pulling. She provides strong healing, team-wide Attack buffs, Defense Ignore, and fits into future Anima, Cosmos, and Lakshana teams.Should You Pull Iroi

Not only that, Iroi is not just another traditional healer. She can enhance the entire team with powerful Attack buffs and also provides revive mechanics for completing the toughest battles, making her one of the most valuable support characters worth pulling. She works well in most team compositions and can remain useful for future content.

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Conclusion 

And that's the end of our best Neverness to Everness Iroi build guide. In this guide, we explained how Iroi kit works, the best Arcs, Module setups, and the best builds you can use to make Iroi your ultimate support character throughout your adventure. If you're looking for a way to master Iroi and quickly upgrade her to her maximum potential, you can use OSLink to access your Neverness to Everness PC sessions directly from your mobile, allowing you to stay connected and continue progressing anytime, even when you're away from your PC.